A Narrative Review of the Potential Roles of Lipid-Based Vesicles (Vesiculosomes) in Burn Management

Burn injuries can have a lasting effect on people’s quality of life, as they negatively impact their physical and mental health. Then, are likely to suffer psychological problems result. A serious problem is that deep burns more challenging treat due slow healing rate susceptibility microbial infection. Conventional topical medications used for burn treatment sometimes ineffective because cannot optimize ability transcutaneous absorption at the targeted site accelerate healing. However, nanotechnology offers excellent prospects developing current medical wound therapies capable addressing issues such low drug stability, water solubility, permeability, bioavailability. The review focuses lipid-based vesicles (vesiculosomes) an example advanced delivery systems, showing potential clinical applications in management. Vesiculosomes may help overcome impediments including bioavailability active agents, offering controlled release drugs, increased fewer side effects, reduced dosing frequency, which will ultimately improve therapeutic efficacy patient compliance. We discuss application various types vesiculosomes liposomes, niosomes, ethosomes, cubosomes, transfersomes, phytosomes therapy, these demonstrate superior skin penetration compared conventional treatment. also highlight noteworthy uses formulation natural products status well future perspectives carriers Furthermore, options currently available market summarized.